Oh boy, you really must be a beginner!
Your hard disc is, usually, partitioned to allow you to save your vital files on the additional drive thus created so that in the event you need to format your primary drive due to infection etc, you can do that without affecting the data stored on the secondary drive!
Usually, one would maintain a dual boot computer like with Windows 98 on the secondary drive, so that you could use the secondary OS to help you format and reinstall the primary OS like Windows XP on the primary drive with the least loss of data etc.; since the secondary OS is a fail-safe that you maintain for emergencies like this.
Actually, other than the Primary OS, you shouldn't be keeping anything else on the primary drive which is the target for all viruses and worms.
You seem to be wanting to commit suicide by wanting to remove the partition and leave yourself wide open!
I'd be uninstalling all other Programs, other than the OS from the Primary drive, and reinstalling on the secondary drive, if I were you. Including my modem driver drivers/dialers/router configurations etc. Because, when the OS is hit by a virus or worm, I'd be safely able to uninstall by formatting the drive and reinstalling over that, without losing anything but the most recent work that would've brought in the virus there anyway.
Hope this helps you from committing the act of suicide you were about to do in ignorance.
All the best.
Cheers